The Canadian Lacrosse League is ready for the 2016 season. This week they announced their schedule, which begins on January 15th when the Barrie Blizzards travel to face the Ohsweken Demons. Every team will play ten games, five home and five away, with the four best teams making the playoffs. All games on on a Friday or a weekend day.
| Day | Date | Visitor | Home | Time | Venue |
| Friday | January 15 | Barrie Blizzard | Ohsweken Demons | 8 pm | Iroquois Lacrosse Arena |
| Saturday | January 16 | Niagara Lock Monsters | Durham Turfdogs | 2 pm | GM Centre |
| Saturday | January 16 | Ohsweken Demons | Southwest Cyclops | 7:30 pm | Syl Apps Community Centre |
| Friday | January 22 | Ohsweken Demons | Durham Turfdogs | 8 pm | GM Centre |
| Friday | January 22 | Niagara Lock Monsters | Southwest Cyclops | 7:30 pm | Syl Apps Community Centre |
| Saturday | January 23 | Barrie Blizzard | Durham Turfdogs | 2 pm | GM Centre |
| Sunday | January 24 | Ohsweken Demons | Barrie Blizzard | 2 pm | Barrie Molson Centre |
| Sunday | January 24 | Southwest Cyclops | Niagara Lock Monsters | 2 pm | Meridian Centre |
| Friday | January 29 | Durham Turfdogs | Ohsweken Demons | 8 pm | Iroquois Lacrosse Arena |
| Friday | January 29 | Barrie Blizzard | Southwest Cyclops | 8 pm | Syl Apps Community Centre |
| Friday | February 5 | Southwest Cyclops | Ohsweken Demons | 7:30 pm | Iroquois Lacrosse Arena |
| Sunday | February 7 | Southwest Cyclops | Barrie Blizzard | 2 pm | Barrie Molson Centre |
| Sunday | February 7 | Durham Turfdogs | Niagara Lock Monsters | 2 pm | Meridian Centre |
| Friday | February 12 | Niagara Lock Monsters | Ohsweken Demons | 7:30 pm | Iroquois Lacrosse Arena |
| Saturday | February 13 | Barrie Blizzard | Durham Turfdogs | 2 pm | GM Centre |
| Saturday | February 13 | Ohsweken Demons | Niagara Lock Monsters | 2 pm | Meridian Centre |
| Sunday | February 14 | Durham Turfdogs | Barrie Blizzard | 2 pm | Barrie Molson Centre |
| Friday | February 19 | Ohsweken Demons | Southwest Cyclops | 7:30 pm | Syl Apps Community Centre |
| Saturday | February 20 | Barrie Blizzard | Niagara Lock Monsters | 2 pm | Meridian Centre |
| Friday | February 26 | Southwest Cyclops | Durham Turfdogs | 8 pm | GM Centre |
| Friday | February 26 | Niagara Lock Monsters | Ohsweken Demons | 7:30 pm | Iroquois Lacrosse Arena |
| Sunday | February 28 | Niagara Lock Monsters | Barrie Blizzard | 2 pm | Barrie Molson Centre |
| Saturday | March 5 | Durham Turfdogs | Southwest Cyclops | 8 pm | Syl Apps Community Centre |
| Sunday | March 6 | Durham Turfdogs | Barrie Blizzard | 2 pm | Barrie Molson Centre |
| Sunday | March 6 | Southwest Cyclops | Niagara Lock Monsters | 2 pm | Meridian Centre |
